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To further investigate cellular signalling pathways that are activated by Y1R signalling and how they change upon BIBO3304 treatment in vivo, we employed an Akt FRET biosensor mouse model validated previously 24, 25 and monitored the dynamic changes of Akt phosphorylation, a central node of metabolic signalling, in BAT by multiphoton microscopy in live animals <a href=http://dapoxetine.buzz>priligy at walgreens</a>
 
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